The match was level with a quarter of an hour left to play, but a Filip Jorgensen error opened the door for Vitinha to give PSG a late advantage. Khvicha Kvaratskhelia then piled on with goals in the 86th and 94th minutes.
Club captain Reece James, less than a week after extending his Chelsea contract through to 2030, is set to spend some time on the sidelines with a hamstring injury, while Malo Gusto missed training through illness this week.
It is not all bad news for the Blues, though, as exciting young winger Estevao is back in the fold, having recovered from a hamstring injury of his own.
How to watch Chelsea vs Paris Saint-Germain
TV channel: In the UK, the game will be televised live on TNT Sports 2, with coverage starting at 7pm ahead of an 8pm kick-off.
Live stream: TNT Sports subscribers can also catch the contest live online via the Discovery+ app and website.
Live blog: You can follow all the action on matchday via Standard Sport’s live blog, with expert analysis from Dom Smith at the ground.
